Basil Rathbone as Sherlock Holmes

Nigel Bruce as Dr. John H. Watson

Patricia Morison as Mrs. Hilda Courtney

Frederick Worlock as Colonel Cavanaugh

Harry Cording as Hamid

Carl Harbord as Inspector Hopkins

Holmes Herbert as Ebenezer Crabtree

Edmund Breon as Julian 'Stinky' Emery

Patricia Cameron as Evelyn Clifford

Mary Gordon as Mrs. Hudson

Ian Wolfe as Commissioner of Scotland Yard

Leyland Hodgson as Tour Guide

Marjorie Bennett as Antique Shop Assistant (uncredited)

William H. O'Brien as Detective at Murder Scene

Frank Baker as Photographer

Sally Shepherd as

Wallace Scott as Joe Cisto

Jack Curtis as Pub Patron (uncredited)

Cyril Delevanti as Convict at Dartmoor Prison (uncredited)

Charlie Hall as Cab Driver (uncredited)

Olaf Hytten as Alfred - Auction House Bookkeeper (uncredited)

Frank Mills as Pub Patron (uncredited)

Lillian Bronson as Minister's Wife (uncredited)

Bobby Hale as Pub Patron (uncredited)

Alexander Pollard as Crabtree's Assistant at Auction (uncredited)