Christian Slater as Charlie "Lucky" Luciano

Costas Mandylor as Frank Costello

Richard Grieco as Benjamin "Bugsy" Siegel

Patrick Dempsey as Meyer Lansky

Lara Flynn Boyle as Mara Motes

Michael Gambon as Don Salvatore Faranzano

Anthony Quinn as Don Giuseppe 'Joe the Boss' Masseria

Robert Z'Dar as Rocco

Chris Penn as Tommy Reina

F. Murray Abraham as Arnold Rothstein

Seymour Cassel as Father Bonotto

Andy Romano as Antonio Luciano

Bianca Rossini as Rosalie Luciano

Anto Nolan as Irish Cop

Joe Viterelli as Joe Profaci

Rodney Eastman as Joey

Karen Russell as Showgirl

Russ Fega as Nathan Citron

Lynette Walden as Cute Debutante

Sharmagne Leland-St. John as Wedding Guest

Cie Allman as Dancer

Titus Welliver as Al Capone

Jennifer Gatti as Secretary

Ava Fabian as Cute Girl