Richard Gere as Richard 'Dixie' Dwyer

Gregory Hines as Delbert 'Sandman' Williams

Diane Lane as Vera Cicero

Lonette McKee as Lila Rose Oliver

Bob Hoskins as Owney Madden

James Remar as Dutch Schultz

Nicolas Cage as Vincent Dwyer

Allen Garfield as Otto 'Abbadabba' Berman

Fred Gwynne as Frenchy Demange

Gwen Verdon as Tish Dwyer

Lisa Jane Persky as Frances Flegenheimer

Maurice Hines as Clay Williams

Julian Beck as Sol Weinstein

Novella Nelson as Madame St. Clair

Laurence Fishburne as Bumpy Rhodes

John P. Ryan as Joe Flynn

Tom Waits as Irving Stark

Ron Karabatsos as Mike Best

Glenn Withrow as Ed Popke

Jennifer Grey as Patsy Dwyer

Wynonna Smith as Winnie Williams

Thelma Carpenter as Norma Williams

Charles "Honi" Coles as Suger Coates

Larry Marshall as Cab Calloway

Joe Dallesandro as Charles 'Lucky' Luciano

Diane Venora as Gloria Swanson

Tucker Smallwood as Kid Griffin

Marc Coppola as Ted Husing

Robert Earl Jones as Stage Door Joe

Sofia Coppola as Child in Street

Tracey Ross as Dancer

Mario Van Peebles as Dancer

Ed O'Ross as Monk

Frederick Downs Jr. as Sullen Man

Woody Strode as Holmes

Bill Graham as J.W.

Dayton Allen as Solly

Kim Chan as Ling

Ed Rowan as Messiah

Leonard Termo as Danny

Brian Tarantina as Vince Hood

Bruce MacVittie as Vince Hood

James Russo as Vince Hood

Giancarlo Esposito as Bumpy Hood

Rony Clanton as Caspar Holstein

Damien Leake as Bub Jewett

Bill Cobbs as Big Joe Ison

Joe Lynn as Marcial Flores

Oscar Barnes as Spanish Henry

Ed Zang as Hotel Clerk

Sandra Beall as Myrtle Fay

Zane Mark as Duke Ellington

Paul Herman as Policeman #1

Randle Mell as Policeman #2

Gregory Rozakis as Charlie Chaplin

Vincent Jerman-Jerosa as James Cagney

Rosalind Harris as Fanny Brice

Jackée Harry as Dancer

Sonya Hensley as Dancer

Valarie Pettiford as Dancer

Kimberly Dorsey as Joan Blondell (uncredited)

Anton Evangelista as Ownie Hood (uncredited)

Nicholas J. Giangiulio as Screen Test Thug (uncredited)

Suzanne Kaaren as The Duchess of Park Avenue (uncredited)

Robin Karfo as Vera's Sidekick / Banville Club (uncredited)

Mark Margolis as Charlie Workman (uncredited)

Naylon Mitchell as Busboy (uncredited)

Ray Negron as Waiter (uncredited)

Kirk Taylor as Cotton Club Waiter (uncredited)

Rick Washburn as Hitman (uncredited)

Linda Gillen as voice (uncredited)