John Wayne as Robert Marmaduke Sangster Hightower

Pedro Armendáriz as Pedro 'Pete' Roca Fuerte

Harry Carey, Jr. as William Kearney ('The Abilene Kid')

Ward Bond as Perley 'Buck' Sweet

Mae Marsh as Mrs. Perley Sweet

Mildred Natwick as The Mother

Jane Darwell as Miss Florie

Guy Kibbee as Judge

Dorothy Ford as Ruby Latham

Ben Johnson as Posse man #1

Charles Halton as Oliver Latham

Hank Worden as Deputy Curly

Jack Pennick as Luke

Fred Libby as Deputy

Michael Dugan as Posse Man #2

Don Summers as Posse Man #3

Gertrude Astor as Saloon Girl (uncredited)

Richard Hageman as Saloon Pianist (uncredited)

Nora Bush as Townswoman (uncredited)

Eva Novak as Townswoman (uncredited)

Charles Soldani as Townsman (uncredited)

Ruth Clifford as Woman in Bar (uncredited)

Jack Curtis as Bartender (uncredited)

Harry Tenbrook as Bartender (uncredited)

Tex Driscoll as Barfly (uncredited)

Jack Kenny as Barfly (uncredited)

Jack Mower as Barfly (uncredited)

Francis Ford as Drunk (uncredited)

Cliff Lyons as Guard at Mojave Tanks (uncredited)

Amelia Yelda as Robert William Pedro Hightower (the Baby) (uncredited)