Shannen Doherty as Beth Hammersmith / Karen Oxford

Julie Benz as Alison Kingsley

Daniel Cosgrove as Mark Lantch

Richard Joseph Paul as Nick Delacroix

Taraji P. Henson as Paige

Aimée Castle as Courtney

Mandy Schaffer as Hillary

Victoria Sanchez as Lisa Bagley

Kate Jackson as The Dean

Alan Fawcett as Ruben

Jessica Goldapple as Kim

Christian Paul as T.J.

Adam MacDonald as Blake

Jonathan Stark as Mr. Hammersmith

Susan Glover as Mrs. Hammersmith

Genevieve Farrell as Young Beth

Sally Taylor-Isherwood as Young Jenny

Elliot Mandelcorn as Beth's Husband

Cecile Cristobal as Melanie Hernandez

Marianne Farley as Joan

Paul Stewart as Minister

Melissa Galianos as Fallbridge Student

Natalie Stechysin as Dawn

Eleanor Noble as Celine

Carole B. Thomas as Policewoman