Rupert Friend as Agent 47

Zachary Quinto as John Smith

Hannah Ware as Katia

Emilio Rivera as Fabian

Rolf Kanies as Dr. Delriego

Thomas Kretschmann as Le Clerq

Dan Bakkedahl as Sanders

Ciarán Hinds as Litvenko

Mona Pirzad as Katia's Mother

Michaela Caspar as Hall of Records Clerk

Jerry Hoffmann as Franco

AngelaBaby as Diana

Jürgen Prochnow as Tobias

William E. Morris as Surveillance Tech

Charlene Beck as Tenement Woman

Michael Bornhütter as Berlin Police Officer #1

Melissa Broughton as Gardens by the Bay Woman with Baby

Nils Brunkhorst as Syndicate Doctor

Alvin Chan as Gardens by the Bay Man #1

Manuel Depta as Russian Soldier

Andrew DiBartolomeo as Gardens by the Bay Man #2

Georg Ebinal as Salzburg Syndicate Operator Driver

Jörg Ellmer as Ruassian Soldier

Waye Leon Goh as Gardens by the Bay Man #3

Matthias Günther as Marine Task Force

Jesse Hergt as Young Agent 47

Florian Hotz as Lead Syndicate Operator

Sebastian Hülk as Garad

Michael Knese as Embassy Marine #2

Felix Koch as Salzburg Syndicate Operator Driver #1

Alrik Kreemke as Salzburg Syndicate Operator #1

Daniel Michael Nelson as Robert - Kid in Elevator

Peter Paes as Salzburg Syndicate Operator Driver #2

Helena Pieske as Young Katia

Markus Ranglack as Russian Agent / Driver

Kira Smidt as Baby Katia

Daniel Stockhorst as John Smith's G-Wagon Driver

Johannes Suhm as Young Litvenko

Eskindir Tesfay as Marine #2

Asuka Tovazzi as Berlin Police Officer #2

Janice Koh Yu-Mei as Robert's Mum

Michael Corcoran as Robert's Dad

Melanie Benna as Businesswoman (uncredited)

David Brückner as Syndicate International Hacker (uncredited)

Dennis Heath as Bystander in Action Scene (uncredited)

Jessica Lois as Woman in Subway Station (uncredited)

Chris Theisinger as S.I. Tactical Ops (uncredited)

Joe Tödtling as Marine (uncredited)

Tomas Jester as Tenement Man

Gillian Tan as Woman in Airport (uncredited)