Dylan O'Brien as Thomas

Kaya Scodelario as Teresa Agnes

Thomas Brodie-Sangster as Newt

Giancarlo Esposito as Jorge

Ki Hong Lee as Minho

Dexter Darden as Frypan

Rosa Salazar as Brenda

Patricia Clarkson as Ava Paige

Aidan Gillen as Janson

Barry Pepper as Vince

Nathalie Emmanuel as Harriet

Alexander Flores as Winston

Jacob Lofland as Aris Jones

Lili Taylor as Mary Cooper

Alan Tudyk as Blondie

Terry Dale Parks as Carl (Masked Man)

Kathryn Smith-McGlynn as Dr. Crawford

Matthew T. Metzler as Barkley

Jenny Gabrielle as Ponytail

David House as Soldier

Lora Martinez-Cunningham as Thomas' Mother

Luke Gallegos as Young Thomas

Shawn Prince as David

Jeremy Becerra as Riley

Matthew Page as Harold (Soldier)

Alex Knight as Aide

Marc Comstock as Med Tech

John Trejo as M3 Soldier

Katherine McNamara as Sonya

Tatanka Means as Joe

Ryan Jason Cook as Nurse

James Burnett as Rebel Sentry

Morse Bicknell as Doctor

Adriana Acosta as Glader (uncredited)

Brian Barela as Bunker Soldier (uncredited)

Laramie Cooley as Abigail (uncredited)

Jetto Dorsainville as WCKD / Bunker Militia (uncredited)

Andrea Good as Ash People (uncredited)

Carma Harvey as Scavenger (uncredited)

Gary Hood as Glader (uncredited)

Keith Jardine as Scavenger Guard (Jim) (uncredited)

Jess King as WCKD Soldier (uncredited)

Martin Palmer as Rave Party Guest (uncredited)

Frank Powers as Soldier (uncredited)

Ben Pronsky as Additional Voices (voice) (uncredited)

James Tyler Robinson as Glader (uncredited)

Gonzalo Robles as Hazmat Soldier (uncredited)

Bryce Romero as Jack (uncredited)

Diego Romero as Scavenger Guard (uncredited)

J. Nathan Simmons as Ash Mob Evacuee (uncredited)

Kaelee Vigil as Civilian (uncredited)

Alexander Wagenman as Kid on Train (uncredited)

Richard Daniel Williams as Right Arm Militia (uncredited)

John Christian Love as Surveillance Room Attendant

Kelly V. Lucio as Glader / Rescued Glader (uncredited)

Tureygua Inaru as Glader