Eddie Redmayne as Newt Scamander

Katherine Waterston as Porpentina 'Tina' Goldstein

Dan Fogler as Jacob Kowalski

Alison Sudol as Queenie Goldstein

Colin Farrell as Percival Graves

Jon Voight as Henry Shaw Sr.

Ron Perlman as Gnarlak

Johnny Depp as Gellert Grindelwald

Zoë Kravitz as Leta Lestrange

Ezra Miller as Credence Barebone

Samantha Morton as Mary Lou Barebone

Carmen Ejogo as Seraphina Picquery

Josh Cowdery as Henry Shaw Jr.

Ronan Raftery as Langdon Shaw

Faith Wood-Blagrove as Modesty Barebone

Jenn Murray as Chastity Barebone

Gemma Chan as Madame Ya Zou

Peter Breitmayer as Gilbert Bingley

Kevin Guthrie as Mr. Abernathy

Sean Cronin as Nearby Criminal

Sam Redford as Customs Official

Akin Gazi as Auror

Todd Boyce as The Announcer

Anne Wittman as Housewife

Andreea Păduraru as Auror 9

Matthew Sim as Photographer 1

Elizabeth Moynihan as Executioner #1

Adam Lazarus as Wizard

Lucie Pohl as Secretary

Tim Bentinck as Witness

Bart Edwards as New York Chief of Police

Brian F. Mulvey as The Watchman

Tristan Tait as Reporter

Tom Clarke Hill as Photographer 2

Cory Peterson as Bank Employee

Jake Samuels as Bank Guard

Max Cazier as Young Man

Dan Hedaya as Red

Christy Meyer as Guide - Inside Macusa

Guy Paul as Auror 2

Walles Hamonde as Auror 10

Dominique Tipper as Auror 1

Leo Heller as Boy with Birthmark

Miles Roughley as Poor Boy

Erick Hayden as Policeman

Paul Birchard as Hobo

Tom Hodgkins as Barker

Ellie Haddington as Mrs. Esposito

Joseph Macnab as Police Officer 1

Martin Oelbermann as Heinrich Eberstadt

Richard Clothier as British Envoy

Christian Dixon as Momolou Wotorson

Richard Hardisty as Auror 4

Miquel Brown as Executioner #2

Wunmi Mosaku as Beryl

Cristian Solimeno as Executioner #3

Matthew Wilson as Sam the Obliviator

Aretha Ayeh as Singer - The Blind Pig Speakeasy

Emmi as Singer - The Blind Pig Speakeasy

Nicholas McGaughey as Australian Wizard

Arinzé Kene as Auror 6

Jane Perry as Bakery Customer

Abi Adeyemi as International Royal Dignitar (uncredited)

Alphonso Austin as Boat Crew (uncredited)

Roy Beck as Senator Shaw's Speechwriter (uncredited)

David J Biscoe as Journalist (uncredited)

Lee Bolton as Photographer (uncredited)

Neil Broome as Gala Dinner Guest (uncredited)

Fanny Carbonnel as Mrs. Goldstein (uncredited)

David Charles-Cully as Gentleman (uncredited)

Craig Davies as New Yorker (uncredited)

Chloe de Burgh as Tenement Woman (uncredited)

Paul Dewdney as New York Journalist (uncredited)

Rudi Dharmalingam as Ranjit (uncredited)

Joshua Diffley as Young Husband (uncredited)

Richard Douglas as Gentleman (uncredited)

Henry Douthwaite as Skender (uncredited)

Dino Fazzani as Factory Worker (uncredited)

Abigayle Honeywill as Criminal (uncredited)

Attila G. Kerekes as New York Citizen (uncredited)

Simon Kerrison as High Society Gentleman / Gala Guest (uncredited)

Denis Khoroshko as Banker Smirnoff (uncredited)

Alan Mandel as Mr. Goldstein (uncredited)

Jorge Leon as Spaniard Ship Passenger (uncredited)

Christine Marzano as Exterminator (uncredited)

Pete Meads as Factory Worker (uncredited)

Dennis O'Donnell as Circus Escapologist (uncredited)

Gino Picciano as Gangster (uncredited)

Jason Redshaw as Higher Class Gentleman (uncredited)

Dave Simon as New York Socialite (uncredited)

Connor Sullivan as Gala Guest (uncredited)

Dan Trotter as Street Vendor (uncredited)

Morgan Walters as Watchman (uncredited)

Anick Wiget as Criminal on 'Wanted' Poster (uncredited)

Reid Anderson as Auror (uncredited)

Tineke Ann Robson as Auror (uncredited)

Cinta Laura Kiehl as Candy Store Girl

Annarie Boor as New Yorker (uncredited)