Dustin Hoffman as Lenny Bruce

Valerie Perrine as Honey Bruce

Jan Miner as Sally Marr

Stanley Beck as Artie Silver

Frankie Man as Baltimore Comic

Rashel Novikoff as Aunt Mema

Gary Morton as Sherman Hart

Guy Rennie as Jack Goldstein

Michele Yonge as Nurse

Kathryn Witt as Girl

Monroe Myers as Hawaiin Judge

John DiSanti as John Santi

Mickey Gatlin as San Francisco Policeman

Martin Begley as San Francisco Judge

Mark Harris as Defense Attorney

Richard Friedman as San Francisco Prosecutor

Lee Sandman as 2nd San Francisco Judge

Jack Nagle as Reverend Mooney

Phil Philbin as New York Plainclothesman

Bruce McLaughlin as New York Judge

Ted Sorel as New York Attorney

Clarence Thomas as New York Attorney

Mike Murphy as New York Prosecutor

Susan Malnik as Kitty (age twelve)

George DeWitt as Comic

Judy LaScala as Chorus Girl

Don Newsome as Connection

Allison Goldstein as Kitty (age one)

Winston Lee as Chinese Waiter

Bridghid Glass as Kitty (age two)

Joe Mencel as Court Reporter

Richard O'Barry as Court Clerk

Beth Challis as Club Owner

Robert Parsons as Chicago Plainclothesman

Cecil Seay as Chicago Plainclothesman

Bob Collins as New York Assistant DA

Lynette Bernay as Girl in Dressing Room (uncredited)

Bob Fosse as The Interviewer (voice) (uncredited)

Phyllis Hyman as Nightclub Patron (uncredited)

Lillian Zuckerman as Nightclub Patron (uncredited)

Mal Jones as New York Court Clerk (uncredited)

David Joseph Martinez as Marine Private (uncredited)

Alan Ormsby as Man in Audience of Cellar Club (uncredited)

Frank Orsatti as Hunter (uncredited)

Glenn R. Wilder as Hunter (uncredited)

Zorita as Nightclub Owner (uncredited)

Cindy Embers as Opening Stripper (uncredited)

Rod Ball as Man in Audience of Cellar Club