Jack Lemmon as Felix Ungar

Walter Matthau as Oscar Madison

Richard Riehle as Detective

Jonathan Silverman as Brucey Madison

Lisa Waltz as Hannah Unger

Mary Beth Peil as Felice

Christine Baranski as Thelma

Jean Smart as Holly

Rex Linn as JayJay

Jay O. Sanders as Leroy

Barnard Hughes as Beaumont

Ellen Geer as Frances Unger Melnick

Doris Belack as Blanche Madison Povitch

Mary Fogarty as Flossie

Alice Ghostley as Esther

Peggy Miley as Millie

Rebecca Schull as Wanda

Florence Stanley as Hattie

Estelle Harris as Flirting Woman

Joaquín Martínez as Truck Driver

Amy Yasbeck as Stewardess

Francesca P. Roberts as Passenger

Amy Parrish as Computer Girl

Liz Torres as Maria

Myles Jeffrey as Little Boy

Carmen Mormino as California State Trooper

Chuck Montgomery as California State Trooper

Earl Boen as Fred

Ron Harper as Jack

Edmund L. Shaff as Ralph

Daisy Velez as Conchita

Beecey Carlson as Waitress

Terry L. Rose as Bartender

Alfred Dennis as Morton

Armando Ortega as Detective #2

Peter Renaday as Justice of the Peace

David Jean Thomas as Bus Driver

Daniel Zacapa as Lead Cop

Cliff Bemis as Dance Partner

Frank Roman as Bellman

Lonnie McCullough as Roadblock Officer

Matt McKenzie as Pilot

Heath Hyche as Policeman

Irene Olga López as Cafe Waitress

Jerry Rector as Detective #3

Martin Grey as Immigration Officer

Michelle Matthow as Wedding Guest

Lou Cutell as Abe

Mark Thomas McGee as Wedding Bartender

Barry Thompson as Passenger

Joanna Sanchez as Passenger

Catherine Paolone as Passenger

Laura Russo as Stewardess #2

Charlie Brewer as

Robert 'Bobby Z' Zajonc as

Darrell Britt as Ball Game Spectator (uncredited)

Beau Lotterman as Red Neck Bar Guy (uncredited)

L. Christian Mixon as Pool Player (uncredited)

Robert Werhan as Diner Patron (uncredited)