Jessica Lange as Margaret Lewin

Halle Berry as Khaila Richards

David Strathairn as Charles Lewin

Cuba Gooding Jr. as Eddie Hughes

Daisy Eagan as Hannah Lewin

Marc John Jefferies as Isaiah

Samuel L. Jackson as Kadar Lewis

Joie Lee as Marie

Regina Taylor as Gussie

LaTanya Richardson Jackson as Caroline Jones

Jacqueline Brookes as Judge Silbowitz

Donovon Ian H. McKnight as Amir

Rikkia A. Smith as Josie

Paulette McDaniels as Ethel

Velma Austin as Rehab Leader

Glenda Starr Kelly as Group Leader

Joan Kohn as Toby Fredericks

Patrick Clear as Bill Fredericks

Gaby Santinelli as Heidi

Mike Bacarella as Liquor Store Clerk

Mike Houlihan as Liquor Store Cop #1

John Beasley as Garbage Man

James 'Ike' Eichling as Garbage Man

James F. Tillett as Intern

John Judd as Paramedic

Cheryl Hamada as ER Nurse

Jackie Taylor as ER Nurse

Valerie Shull as Mrs. Ianelli

Laura Cerón as NICU Woman

Jackie Samuel as NICU Nurse

Deanna Dunagan as Dr. Goldstein

Mike Nussbaum as Dr. Jamison

Margaret Travolta as Sandra Harris

Eddie Bo Smith Jr. as Alley Junkie

Jaqueline Fleming as File Cabinet Girl

Sibyl Offutt as Tenement Woman

Greg Hollimon as Tenement Man

Rick Worthy as Alley Man

Torrence W. Murphy as Alley Man

Shelia-Marie Robinson as Inmate

LaTaunya Bounds as Inmate

Tamara Rutledge as Inmate

Valeri Ross as Day Care Teacher

Jacqueline Williams as Day Care Worker

Ora Jones as Day Care Woman

Nicholas Foster as Boy at Swings

Thomica Laquice Simmons as Neighbor Girl

Evan Lionel as Paramedic #2

Jennifer Crystal Foley as Park Nanny