Renée Zellweger as Emily Jenkins

Jodelle Ferland as Lillith Sullivan

Ian McShane as Detective Mike Barron

Bradley Cooper as Douglas J. Ames

Adrian Lester as Wayne

Kerry O'Malley as Margaret Sullivan

Callum Keith Rennie as Edward Sullivan

Cynthia Stevenson as Nancy

Alexander Conti as Diego

Philip Cabrita as Javier

Vanesa Tomasino as Javier's Wife

Mary Black as Custody Judge

Domenico D'Ambrosio as Domenico D'Ambrosio

Benita Ha as Therapist

J. Winston Carroll as Judge

Michael Bean as Co-Worker

Lesley Ewen as Co-Worker

David Patrick Green as Chief Psychiatrist

Dee Jay Jackson as Bus Driver

Taya Calicetto as Young Emily

Alisen Down as Emily's Mother

Darryl Quon as Inmate

Suzanne Bastien as Nurse

Jane Braithwaite as Nurse

Colin Lawrence as Police Sergeant

Fran Gebhard as Coordinator

Dagmar Midcap as News Anchor

Bill Mondy as Interviewer

Andrew Airlie as Doctor

Sarah-Jane Redmond as Barron's Wife

Charles Zuckermann as Demon Person

Yvonne Valdez as Mrs. Lynch

Paul Duchart as Priest

Daniel Bacon as Businessperson

Darren E. Scott as Young Cop

Dalias Blake as Detention Center Cop

Phillip Mitchell as Lead Guard

Fulvio Cecere as Fire Marshall