Kelly Hu as Maizy (voice)

Wendie Malick as Sheriff Kern (voice)

Matthew Lillard as Shaggy Rogers (voice)

Josh Keaton as Levi (voice)

Mindy Cohn as Velma Dinkley (voice)

Grey DeLisle as Daphne Blake (voice)

Jeff Bennett as Mr. Bumpy / Gravekeeper / Jake (voice)

Steve Blum as Cornfield Clem / Abner (voice)

Frank Welker as Scooby-Doo / Fred Jones (voice)

Gary Anthony Williams as Mayor Husk (voice)