Danny Glover as Silas (segment "Long Black Song")

Wesley Snipes as George Du Vaul (segment "The Boy Who Painted Christ Black")

Lorraine Toussaint as Philomena (segment "The Reunion")

Tate Donovan as David (segment "Long Black Song")

Norman D. Golden II as Aaron (segment "The Boy Who Painted Christ Black")

Susanna Thompson as Beth Ann (segment "The Boy Who Painted Christ Black")

Jasmine Guy as Elna Du Vaul (segment "The Boy Who Painted Christ Black")

Tina Lifford as Sarah (segment "Long Black Song")

Carl Lumbly as Cal (segment "The Boy Who Painted Christ Black")

Bennet Guillory as Willie (segment "The Boy Who Painted Christ Black")

Danny Kamin as Mr. Harper (segment "Long Black Song")

Rae'Ven Larrymore Kelly as Lara (segment "The Boy Who Painted Christ Black")

Timothy Carhart as Prof. Daniel (segment "The Boy Who Painted Christ Black")

Summer Ross Jefferson as Young Philomena #1 (segment "The Boy Who Painted Christ Black")

Vanessa Bell Calloway as Miss Williams (segment "The Boy Who Painted Christ Black")

Winter Elaine Jefferson as Young Philomena #2 (segment "The Boy Who Painted Christ Black")

Amanda Addison as Young Beth Ann (segment "The Boy Who Painted Christ Black")

Kevin Jamal Woods as Clyde (segment "The Boy Who Painted Christ Black")

Ruth Beckford as Mrs. McClaren (segment "The Boy Who Painted Christ Black")

Yolanda King as Mrs. Crawford (segment "The Boy Who Painted Christ Black")

Douglas Cunningham as Drummer