Dylan O'Brien as Thomas

Kaya Scodelario as Teresa Agnes

Thomas Brodie-Sangster as Newt

Ki Hong Lee as Minho

Dexter Darden as Frypan

Rosa Salazar as Brenda

Giancarlo Esposito as Jorge

Will Poulter as Gally

Aidan Gillen as Janson

Patricia Clarkson as Ava Paige

Barry Pepper as Vince

Walton Goggins as Lawrence

Nathalie Emmanuel as Harriet

Jacob Lofland as Aris Jones

Katherine McNamara as Sonya

Dylan Smith as Jasper

Jake Curran as WCKD Lieutenant

Dylan Kriek as Co Conductor

Scot Cooper as Station Chief

Kazi Maubert as Immune Child

Bart Fouche as Engineer

Greg Kriek as Co-Conductor

Paul du Toit as Berg Pilot

Liza Scholtz as Nurse

Shai Lun Choo as Little Girl

Fiona Ramsay as Board Member

Paul Hampshire as Soldier

Nathan Barris as Soldier

Drikus Volschenk as Team Leader

Clayton Evertson as WCKD Operator

Emily Child as Infected Woman

Dale Jackson as Holding Area Guard

Armando De Leca as WCKD Guard

Paul Lazenby as Guard (uncredited)

Parm Soor as Board Member (uncredited)

Ryan Higgins as Extra (uncredited)