Antonio Banderas as Puss in Boots (voice)

Salma Hayek Pinault as Kitty Softpaws (voice)

Harvey Guillén as Perrito (voice)

Wagner Moura as Wolf (voice)

Florence Pugh as Goldilocks (voice)

Olivia Colman as Mama Bear (voice)

Ray Winstone as Papa Bear (voice)

Samson Kayo as Baby Bear (voice)

John Mulaney as Jack Horner (voice)

Da'Vine Joy Randolph as Mama Luna (voice)

Anthony Mendez as Doctor (voice)

Kevin McCann as Ethical Bug (voice)

Bernardo de Paula as Governor / Little Boy's Father / Male Partier (voice)

Betsy Sodaro as Jo Serpent / Additional Baker's Dozen Gang Member (voice)

Artemis Pebdani as Jan Serpent (voice)

Conrad Vernon as Gingy (voice)

Cody Cameron as Pinocchio (voice)

Kailey Crawford as Little Goldi (voice)

Al Rodrigo as Bartender (voice)

Bob Persichetti as Ohhh Cat (voice)

Miguel Matrai as Little Boy (voice)

Pilar Uribe as Governor's Assistant / Female Partier (voice)

Heidi Gardner as Last Baker (voice)

Joel Crawford as Band Member / Baker's Dozen Gang Member (voice)

Januel Mercado as Band Member / Baker's Dozen Gang Member (voice)

James Ryan as Little Jack Audience Member / Baker's Dozen Gang Member (voice)

Natalia Cronembold as Waitress / Baker's Dozen Gang Member (voice)

Paul Fisher as Additional Baker's Dozen Gang Member (voice)

Aydrea Walden as Additional Baker's Dozen Gang Member (voice)