Sam Worthington as Jake Sully

Zoe Saldaña as Neytiri

Sigourney Weaver as Kiri

Stephen Lang as Colonel Miles Quaritch

Kate Winslet as Ronal

Cliff Curtis as Tonowari

Joel David Moore as Norm Spellman

CCH Pounder as Mo'at

Edie Falco as General Frances Ardmore

Jemaine Clement as Dr. Ian Garvin

Giovanni Ribisi as Parker Selfridge

Britain Dalton as Lo'ak

Jamie Flatters as Neteyam

Trinity Bliss as Tuktirey 'Tuk'

Jack Champion as Miles 'Spider' Socorro

Brendan Cowell as Mick Scoresby

Bailey Bass as Tsireya

Filip Geljo as Aonung

Duane Evans Jr. as Rotxo

Dileep Rao as Dr. Max Patel

Matt Gerald as Recom Wainfleet

Robert Okumu as Ta'unui Olecthan

Jennifer Stafford as Ta'unui Tsahik

Keston John as Tarsem

Kevin Dorman as Recom Mansk

Alicia Vela-Bailey as Recom Zdinarsik

Sean Anthony Moran as Recom Fike

Andrew Arrabito as Recom Prager

Johnny Alexander as Recom Ja

Kim Do as Recom Zhang

Victor T. Lopez as Recom Lopez

Maria Walker as Recom Walker

Phil Brown as Stringer

Jocelyn Christian as Bio Lab Tech

Joel Tobeck as Neuroscientist

Moana Ete as Female Med-Tech

Phil Peleton as Male Med-Tech

Jamie Landau as Metkayina Warrior

Jim Moore as Mako Sub #1 Pilot

Benjamin Hoetjes as Mako Sub #1 Gunner

Nikita Tu Bryant as Mako Sub #2 Pilot

Anthony Ahern as Mako Sub #2 Gunner

Shane Rangi as Matador Co-Pilot

Rick Lucas as Kestrel Pilot

Tanya Drewery as Neurotech #1

Ava Diakhaby as Neurotech #2

Isaac Te Reina as Sea Dragon First Mate

Eric Farmer as Crabsuit Pilot

Philip Mtambo as Skel Trooper

Daniel Lough as Spider Double

Cruz Moir as Young Spider

Alex Lucas as Toddler Spider

Scarlett Fernandez as Young Kiri

Chloe Coleman as Young Lo'ak

Jeremy Irwin as Young Neteyam

Jake McLean as Na'vi (uncredited)

CJ Jones as Metkayina Interpreter (uncredited)