Robert De Niro as Walt Koontz

Philip Seymour Hoffman as Rusty

Barry Miller as Leonard Wilcox

Chris Bauer as Jacko

Skipp Sudduth as Tommy

Wilson Jermaine Heredia as Cha-Cha

Nashom Benjamin as Amazing Grace

Scott Allen Cooper as Ivana

Rory Cochrane as Pogo

Daphne Rubin-Vega as Tia

Vincent Laresca as Raymond Camacho

Karina Arroyave as Amber

John Enos III as Sonny

Jude Ciccolella as Detective Noonan

Mina Bern as Mrs. Spivak

Wanda De Jesus as Karen

Madhur Jaffrey as Dr. Nirmala

Mark Margolis as Vinnie

Shiek Mahmud-Bey as Vance

Luis Saguar as Mr. Z

Kyle Rivers as LeShaun

Sammy Rhee as Mr. Pim

Hyunsoo Lee as Mrs. Pim

Richie LaMontagne as Carmine

Penny Balfour as Cristal

Winter Ave Zoli as Tasha

Raven O. as Notorious F.A.G.

Joey Arias as Stormy

Jackie Beat as Gypsy

Blake Willett as Cop

Ingrid Rivera as Cop

Craig Braun as Paulie

John Doumanian as Mr. Terzola

Melissa Osborn as Tourist

John Contratti as Customer

Stacy Highsmith as Denise

Rod Rodriguez as Lesbian

Alice Williams as Lesbian

Antonette Schwartzberg as Mrs. Terzola

Hamilton De Oliveira as Hotel Janitor

Logan McCall as EMS Technician

John Mack as EMS Technician

John R. Corcoran as Physical Therapist

Matt Merchant as Man in Crowd

Kevin Aviance as Singer

CoCo LaChine as Singer

José Ángel García as Singer

Bruce Roberts as Singer

Al Marz as Cristal's Boyfriend

Michelle Robinson as Dancer

Nina von Arx as Dancer

Larry Marx as Bar Patron

Mitchell Lichtenstein as Gay Republican Spokesperson

John Fink as Gay Republican Lawyer

Bret Kropp as Drag Queen

Cooley as Cop

Constance Boardman as Reporter

Lucy Cerezo-Scully as Paramedic

Al Thompson as Paramedic

Victor Rasuk as Kid from the Neighborhood (uncredited)

Ava Lee Scott as Working Girl (uncredited)

Christian Boeving as Max (uncredited)

Vava Buitenkant as Hooker (uncredited)

Natalie Carter as Neighbor (uncredited)

Michael Harkins as Drag Pageant Contestant (uncredited)

Denice De Jon Nortez as Tango Dancer (uncredited)

Lois Sach as Drag Show Audience Member (uncredited)