Justin Theroux as Jan Jürgen

Steve Coogan as Damien Cockburn

Robert Downey Jr. as Kirk Lazarus

Ben Stiller as Tugg Speedman

Jack Black as Jeff Portnoy

Bill Hader as Rob Slolom

Nick Nolte as Four Leaf Tayback

Jimmy Rich as Drake 'The Stick' Longwood

Jay Baruchel as Kevin Sandusky

Brandon T. Jackson as Alpa Cino

Janeane Garofalo as Heidi Bivens

Tom Cruise as Les Grossman