Spencer Tracy as James P. Curtayne

Pat O'Brien as Det. Vincent Ricks

Diana Lynn as Virginia 'Ginny' Curtayne

John Hodiak as District Attorney Louis Barra

Eduardo Ciannelli as Sol 'Knuckles' Lanzetta

James Arness as John Fordman 'Johnny' O'Hara

Yvette Duguay as Mrs. Katrina Lanzetta

Jay C. Flippen as Sven Norson

William Campbell as Frank Korvac

Richard Anderson as Jeff Chapman

Arthur Shields as Mr. O'Hara

Louise Lorimer as Mrs. Peg O'Hara

Henry O'Neill as Judge Keating

Ann Doran as Betty Clark, Policewoman

Emile Meyer as Captain Tom Mulvaney

Regis Toomey as Fred Colton, Police Sound Man

Katherine Warren as Mrs. William Sheffield (as Katharine Warren)

John Albright as Waiter (uncredited)

Tony Barr as Little Wolfie (uncredited)

Richard Bartlett as Tony Korvac (uncredited)

Brooks Benedict as Gambler (uncredited)

Leonard Bremen as Harry (uncredited)

Charles Bronson as Angelo Korvac (uncredited)

Mae Clarke as Receptionist (uncredited)

Michael Tolan as Vincent Korvac (as Lawrence Tolan) (uncredited)

Peter Mamakos as James Korvac (uncredited)

Sailor Vincent as William Sheffield (uncredited)

Ned Glass as Preliminary Hearing Judge (uncredited)

Bill Fletcher as Pete Korvac (uncredited)

Jack Kruschen as Uniformed Detective (uncredited)

William Schallert as Intern with Ambulance (uncredited)