Adam Driver as Paterson

Golshifteh Farahani as Laura

Nellie as Marvin

Rizwan Manji as Donny

Barry Shabaka Henley as Doc

William Jackson Harper as Everett

Chasten Harmon as Marie

Method Man as Method Man

Dominic Liriano as Boy on Bus 1

Jaden Michael as Boy on Bus 2

Trevor Parham as Sam

Troy T. Parham as Dave

Brian McCarthy as Jimmy

Frank Harts as Luis

Luis Da Silva, Jr. as Blood in Convertible

Kacey Cockett as Woman in Red

Kara Hayward as Female Student

Jared Gilman as Male Student

Sterling Jerins as Young Poet

Johnnie Mae as Doc's Wife

Masatoshi Nagase as Japanese Poet

Helen-Jean Arthur as Older Woman 1

Joan Kendall as Older Woman 2

Owen Asztalos as Small Boy 1

Jorge Vega as Small Boy 2

Sophia Muller as Small Girl

Mirla Pereira as Woman Drinking Coffee on the Bus (uncredited)

James Van Treuren as Coverall Man (uncredited)

Martin Van Treuren as Coverall Man (uncredited)

Volieda Webb as Bar Patron (uncredited)