Mary Elizabeth Mastrantonio as Jean Ellison

John Slattery as Ed Ellison

Lacey Chabert as Brooke Ellison

Vanessa Marano as Young Brooke Ellison

Jenson Goins as Young Kysten Ellison

Devon Gearhart as Young Reed Ellison

Lauren Barrett as Older Kysten Ellison

Ryan P. Hudson as Reed Ellison

Luke Flynn as Jan Djilas

Terrence Gibney as Mr. Barnes

Sabah as Cara

Jerry Lee Leighton as Mr. Linski

Ramona Tyler as Bobbi

Melinda Walsh as Barbara

Judy Leavell as Muriel

Bernard Hocke as Neurosurgeon #1

Wilbur Fitzgerald as Neurosurgeon #2

Marco St. John as Literature Professor

Eugenie Bondurant as Patio Mom

Michael Arata as Paramedic

John McConnell as Mr. Jacobs

Will Reeve as Young David

Lara Grice as Home Room Teacher

Lance E. Nichols as Play Off Official

Dana Reeve as English Professor

Scott Shilstone as David

CiCi Hedgpeth as Young Girl

Tom Raley as ICU Doctor

William Carroll Schilling as Priest

Anne Ewen as Nurse #1

Charlie Detraz as Surgeon

Laura-Shay Griffin as Intern

Deneen Tyler as Receptionist

Wayne Ferrara as Banker

Nathaniel Colin as Opponent

Francine Segal as Female Dean

Pat Hazell as Jim

Joe M. Henry as Jon

Robyn Nolting as Night Nurse #1

Jaqueline Fleming as Night Nurse #2

Paul Schierhorn as Biology Professor

William G. Clark as Professor #1

John Maxwell as Professor #2

John P. Fertitta as Ray

Ron Flagge as Respiratory Therapist

Neal Rivet as Student #1

Stephanie Lysaght as Student #2

Felix Favaloro as Student #3

Belle Caplis as Student #4

Mikki Val as Nurse #2