Hugh Beaumont as Michael Shayne

Cheryl Walker as Phyllis Hamilton

Ralph Dunn as Det. Sgt. Pete Rafferty

Paul Bryar as Tim Rourke

Charles C. Wilson as Chief Gentry (as Charles Wilson)

Douglas Fowley as Doc H. C. Patterson

Gordon Richards as Burton Stallings

Charles Quigley as Arch Dubler

Julia McMillan as Lucille

Marie Hannon as Helen Stallings / Barbara Brett

Lee Bennett as Whit Marlowe

Henry Hall as Dr. F. C. Porter

Fred Aldrich as Asylum Orderly

Chet Brandenburg as Patient

John Cason as Club Bouncer

Milton Kibbee as Joe Morell

Bob Reeves as Police Officer

Jack Roper as Club Bouncer

Gene Roth as Asylum Orderly