Sanaa Lathan as Alexa Woods

Lance Henriksen as Charles Bishop Weyland

Ian Whyte as Scar

Raoul Bova as Sebastian de Rosa

Ewen Bremner as Graeme Miller

Colin Salmon as Maxwell Stafford

Tommy Flanagan as Mark Verheiden

Joseph Rye as Joe Connors

Agathe de La Boulaye as Adele Rousseau

Carsten Nørgaard as Rusten Quinn

Sam Troughton as Thomas Parks

Petr Jákl as Stone

Pavel Bezděk as Bass

Kieran Bew as Klaus

Carsten Voigt as Mikkel

Jan Filipenský as Boris

Adrian Bouchet as Sven

Andy Lucas as Juan Ramirez

Liz May Brice as Supervisor

Glenn Conroy as Technician

Eoin McCarthy as Karl

Karima McAdams as Sacrificial Maiden

Tom Woodruff Jr. as Grid

Joseph Balderrama as High Priest (uncredited)

Alec Gillis as Technician (uncredited)

Alex Lorre as Spaceship Crew (uncredited)

Jack Pierce as Co-Pilot (uncredited)