Bryan Cranston as Chief (voice)

Koyu Rankin as Atari Kobayashi (voice)

Bob Balaban as King (voice)

Edward Norton as Rex (voice)

Bill Murray as Boss (voice)

Jeff Goldblum as Duke (voice)

Kunichi Nomura as Mayor Kobayashi (voice)

Fisher Stevens as Scrap (voice)

Akira Takayama as Major Domo (voice)

Greta Gerwig as Tracy Walker (voice)

Ken Watanabe as Head Surgeon (voice)

Frances McDormand as Interpreter Nelson (voice)

Nijiro Murakami as Editor Hiroshi (voice)

Harvey Keitel as Gondo (voice)

Liev Schreiber as Spots (voice)

Scarlett Johansson as Nutmeg (voice)

Tilda Swinton as Oracle (voice)

Akira Ito as Professor Watanabe (voice)

F. Murray Abraham as Jupiter (voice)

Courtney B. Vance as Narrator (voice)

Yoko Ono as Assistant-Scientist Yoko-ono (voice)

Mari Natsuki as Auntie (voice)

Yojiro Noda as News Anchor (voice)

Frank Wood as Simul-Translate Machine (voice)

Roman Coppola as Igor (voice)

Anjelica Huston as Mute Poodle (voice)

Kara Hayward as Peppermint (voice)

Satoshi Yamazaki as Taiko Drummer (voice)

Gen Ueda as Taiko Drummer (voice)

Ryuhei Matsuda as Junior Scientist 4 / Bartender (voice)

Jun Takahashi as Mission Control Drone Pilot (voice)

Edward Bursch as Owl (voice)

Luli Shioi as Mission Control Technician (voice)

Erica Dorn as Mission Control Technician (voice)

Chinami Narikawa as Mission Control Technician (voice)

Chris Benz as Aboriginal Dog (voice)

Alex Orman as Aboriginal Dog (voice)

J. Wurster as Aboriginal Dog (voice)

Jake Ryan as Junior-Interpreter Ernie (voice)

Takayuki Yamada as Junior Scientist 1 (voice)

Kozue Akimoto as Junior Scientist 2 (voice)

Shota Matsuda as Junior Scientist 3 (voice)

Kiyotaka Mizukoshi as Election Night Tabulator (voice)

Elaiza Ikeda as Punk Girl (voice)

Ryuhei Nakadai as Surgical Assistant (voice)

Shin Mononobe as Surgical Assistant (voice)

Ikunosuke as Daily Manifesto Student (voice)

Taichi Kodama as Daily Manifesto Student (voice)

Karin Okoso as Daily Manifesto Student (voice)