Kevin Dorman as Chris Redfield (voice)

Matthew Mercer as Leon S. Kennedy (voice)

Erin Cahill as Rebecca Chambers (voice) / Rebecca Chambers (motion capture)

John DeMita as Glenn Arias (voice)

Fred Tatasciore as Diego Gomez (voice)

Cristina Valenzuela as Maria Gomez (voice)

Arif S. Kinchen as D.C. (voice)

Kari Wahlgren as Nadia (voice)

Arnie Pantoja as Damian (voice)

Alexander Polinsky as Patricio (voice)

Jason Faunt as Aaron (voice) / Leon S. Kennedy (motion capture)

Mary Elizabeth McGlynn as Zack White (voice)

Karen Strassman as Kathy White (voice)

Fryda Wolff as Patricio's Wife (voice)

Jason Hightower as Captain (voice)

Darin De Paul as Zombie (voice)

Orion Acaba as Soldier (voice)

Brian T. Delaney as Soldier (voice)

Tony Oliver as Soldier (voice)

Bridget Hoffman as Additional Voices (voice)

Rif Hutton as Additional Voices (voice)

Misty Lee as Additional Voices (voice)

Reuben Langdon as Chris Redfield (motion capture)

Dante Carver as D.C. (motion capture)

Hiroko Yashiki as Motion Capture Performer

Akihiko Sai as Motion Capture Performer

David Vincent as Soldier (voice)