Grey DeLisle as Wonder Woman / Giganta / Kogrugarian (voice)

Mae Whitman as Barbara Gordon / Batgirl / Speed Queen (voice)

Yvette Nicole Brown as Amanda Waller (voice)

Tara Strong as Harley Quinn / Poison Ivy (voice)

Anais Fairweather as Supergirl (voice)

Dean Cain as Jonathan Kent (voice)

Helen Slater as Martha Kent (voice)

Greg Cipes as Beast Boy (voice)

John DiMaggio as Gorilla Grodd / Wildcat (voice)

Teala Dunn as Bumblebee / Artemis (voice)

Ashley Eckstein as Cheetah (voice)

Nika Futterman as Hawkgirl (voice)

Tania Gunadi as Lady Shiva (voice)

Josh Keaton as Barry Allen / Hal Jordan (voice)

Tom Kenny as Commissioner Gordon (voice)

Misty Lee as Big Barda / Mad Harriet (voice)

Stephanie Sheh as Katana (voice)

April Stewart as Granny Goodness / Stompa (voice)

Fred Tatasciore as Killer Croc / Percy (voice)