Timothée Chalamet as Paul Atreides

Rebecca Ferguson as Lady Jessica Atreides

Oscar Isaac as Duke Leto Atreides

Jason Momoa as Duncan Idaho

Stellan Skarsgård as Baron Vladimir Harkonnen

Stephen McKinley Henderson as Thufir Hawat

Josh Brolin as Gurney Halleck

Javier Bardem as Stilgar

Sharon Duncan-Brewster as Dr. Liet Kynes

Chang Chen as Dr. Wellington Yueh

Dave Bautista as Beast Rabban Harkonnen

David Dastmalchian as Piter de Vries

Zendaya as Chani

Charlotte Rampling as Reverend Mother Mohiam

Babs Olusanmokun as Jamis

Benjamin Clémentine as Herald of the Change

Souad Faress as Bene Gesserit Sister

Golda Rosheuvel as Shadout Mapes

Roger Yuan as Lieutenant Lanville

Seun Shote as Arrakeen Residency Gardener

Neil Bell as Sardaukar Bashar

Oliver Ryan as Hawat Specialist

Stephen Collins as Harkonnen Trooper

Charlie Rawes as Harkonnen Trooper

Richard Carter as Harkonnen Trooper

Benjamin Dilloway as Sardaukar Assassin

Elmi Rashid Elmi as Shamir

Tachia Newall as Tanat

Gloria Obianyo as Female Fremen

Fehinti Balogun as Male Fremen

Dora Kápolnai-Schvab as Baron Servant

Joelle as Baron Servant

Jimmy Walker as Atreides Lieutenant

Paul Bullion as Sardaukar Soldier

Milena Sidorova as Human Spider Proxy

János Timkó as Harkonnen Guard

Jean Gilpin as Bene Gesserit Ancestor (voice)

Marianne Faithfull as Bene Gesserit Ancestor (voice)

Ellen Dubin as Bene Gesserit Ancestor (voice)

Károly Baksai as Atreides Soldier (uncredited)

Björn Freiberg as Leto Officer (uncredited)

Balázs Megyeri as Sardaukar Soldier (uncredited)

Michael Nardone as Gurney Sergeant (uncredited)

Duncan Pow as Hawat Officer (uncredited)

Ferenc Iván Szabó as Leto Officer (uncredited)

Elemér Szatmári as Harkonnen Medic (uncredited)

Peter Sztojanov, Jr. as Sardaukar Soldier (uncredited)

István Áldott as Sardaukar Soldier (uncredited)