Neve Campbell as Sidney Prescott

David Arquette as Dewey Riley

Courteney Cox as Gale Weathers

Patrick Dempsey as Mark Kincaid

Scott Foley as Roman Bridger

Lance Henriksen as John Milton

Matt Keeslar as Tom Prinze

Jenny McCarthy-Wahlberg as Sarah Darling

Emily Mortimer as Angelina Tyler

Parker Posey as Jennifer Jolie

Deon Richmond as Tyson Fox

Kelly Rutherford as Christine Hamilton

Liev Schreiber as Cotton Weary

Patrick Warburton as Steven Stone

Jamie Kennedy as Randy Meeks

Roger L. Jackson as Ghostface (voice)

Julie Janney as Moderator

Richmond Arquette as Student

Nancy O'Dell as Female Reporter

Ken Taylor as Male Reporter

Lynn McRee as Maureen Prescott

Roger Corman as Studio Executive

Josh Pais as Wallace

John Embry as Stage Security Guard

Lawrence Hecht as Neil Prescott

Lisa Beach as Studio Tour Guide

Kevin Smith as Silent Bob

Jason Mewes as Jay

Erik Erath as Stan

Daniel K. Arredondo as Office Security Guard

Lisa Gordon as Waitress

Heather Matarazzo as Martha Meeks

Carrie Fisher as Bianca Burnette

C.W. Morgan as Hank Loomis

Beth Toussaint as Female Caller (voice)

Wes Craven as Man with Video Camera on Studio Tour (uncredited)

Strawberry Fields as Tourist (uncredited)