Joel McCrea as William Frederick 'Buffalo Bill' Cody

Maureen O'Hara as Louisa Frederici

Linda Darnell as Dawn Starlight

Thomas Mitchell as Ned Buntline

Edgar Buchanan as Sgt. Chips McGraw

Anthony Quinn as Chief Yellow Hand

Moroni Olsen as Sen. Frederici

Frank Fenton as Murdo Carvell

Matt Briggs as General Blazier

George Lessey as Mr. Schyler Vandervere

Sidney Blackmer as Theodore Roosevelt (uncredited)

Evelyn Beresford as Queen Victoria (uncredited)