Margot Robbie as Harley Quinn

Idris Elba as Bloodsport

John Cena as Peacemaker

Joel Kinnaman as Colonel Rick Flag

Sylvester Stallone as King Shark (voice)

Viola Davis as Amanda Waller

David Dastmalchian as Polka-Dot Man

Daniela Melchior as Ratcatcher 2

Michael Rooker as Savant

Jai Courtney as Captain Boomerang

Peter Capaldi as Thinker

Alice Braga as Sol Soria

Pete Davidson as Blackguard

Joaquín Cosío as Mayor General Mateo Suarez

Juan Diego Botto as Presidente General Silvio Luna

Storm Reid as Tyla

Nathan Fillion as T.D.K.

Taika Waititi as Ratcatcher

Steve Agee as John Economos / On-Set King Shark

Sean Gunn as Weasel / Calendar Man

John Ostrander as Doctor Fitzgibbon

Flula Borg as Javelin

Mayling Ng as Mongal

Stephen Blackehart as Briscoe

Tinashe Kajese as Flo Crawley

Jennifer Holland as Emilia Harcourt

Fernando Martinez as Sliced Dome Soldado

Dee Bradley Baker as Sebastian (voice)

Natalia Safran as Kaleidoscope

Jared Leland Gore as Double Down

Rey Hernandez as Teniente

Ray Benitez as Coronel

Reinaldo Faberlle as Large Guerrilla

Jonathan Fritschi as Delicious Hot Dog Guerrilla

Josh Ventura as Astronaut

Gerardo Davila as General Vera

Mikaela Hoover as Camila

Lynne Ashe as Polka-Dot Man's Mom

Julio Cesar Ruiz as Milton

J.R. Adduci as Road Block Soldado

Curtis Lyons Jr. as Road Block Soldado #3

Maya Le Clark as Young Cleo

Elideusa Gomes Almeida as La Gatita Presents Traditional Corto Maltese Dancer

Shanna Kernan as La Gatita Presents Traditional Corto Maltese Dancer

Bridget Taylor as La Gatita Presents Traditional Corto Maltese Dancer

Monica Rivera as La Gatita Presents Traditional Corto Maltese Dancer

Andrea Andrade as La Gatita Waitress

Giovanni Rodriguez as Texting Torturer

Giovannie Cruz as Isabella

Sergio Carlo as Isabella's Second

Edgar Zanabria as Torn-In-Half Soldado

Grecia Balboa as Security Dispatcher

Kenneth Trujillo as Bespectacled Soldado

Randy Havens as Star-Crossed Man

Michelle Civile as Star-Crossed Woman

Gabrielle Manning as Star-Crossed Kid

Michael Aaron Milligan as Star-Crossed Dude

Diany Rodriguez as Star-Crossed Gal

Teresita Mans as Star-Crossed Lady

Terence Rosemore as Crew Chief

Lloyd Kaufman as Dancing La Gatita Bar Patron (uncredited)

Pom Klementieff as La Gatita Amable Dancer (uncredited)

Victoria Paige Watkins as Tiff (uncredited)