Tyrone Power as Jesse Woodson James

Henry Fonda as Frank James

Nancy Kelly as Zerelda "Zee" Cobb

Randolph Scott as Marshall Will Wright

Henry Hull as Major Rufus Cobb

Slim Summerville as Jailer

J. Edward Bromberg as George Runyan

Brian Donlevy as Barshee

John Carradine as Bob Ford

Donald Meek as McCoy

Johnny Russell as Jesse James Jr.

Jane Darwell as Mrs. Samuels - Jesse's mother

Charles Tannen as Charles Ford

Claire Du Brey as Mrs. Bob Ford

Willard Robertson as Clarke

Harold Goodwin as Bill

Ernest Whitman as Pinkie

Eddy Waller as Deputy

Paul E. Burns as Hank

Spencer Charters as Minister

Arthur Aylesworth as Tom Colson

Charles Middleton as Doctor

Charles Halton as Heywood

George Chandler as Roy

Harry Tyler as Farmer

Virginia Brissac as Boy's Mother

Edward LeSaint as Judge Rankin

John Elliott as Judge Mathews

Erville Alderson as Old Marshall

George P. Breakston as Farmer Boy

Lon Chaney Jr. as One Of James Gang

Carol Adams as Minor Role (uncredited)

Donald Douglas as Infantry Captain (uncredited)

James Flavin as Cavalry Captain (uncredited)

Sam Garrett as Rider / Roper (uncredited)

Wylie Grant as Barshee's Henchman

Harry Holman as Engineer (uncredited)

Kenner G. Kemp as Union Soldier (uncredited)

Leonard Kibrick as Boy (uncredited)

Sidney Kibrick as Boy (uncredited)

Ethan Laidlaw as Barshee's Henchman (uncredited)

Tom London as Soldier (uncredited)

George O'Hara as Teller (uncredited)

Paul Sutton as Lynch - Barshee's Henchman (uncredited)