Jon Hamm as Will Beam

Catherine Keener as Donna Beam

John Ortiz as Daniel Kalman

Nick Offerman as Henry Greer

James Le Gros as Patrick Beam

Bruce Dern as Ronnie Ashemore

Ellen Burstyn as Helen Greer

Amber Tamblyn as Bethany Ashemore

Annalise Basso as Tallie Beam

Jennifer Mudge as Caitlin

Joanna Going as Marge

Arye Gross as Riley O'Bryan

Beth Grant as Anna O'Bryan

Hugo Armstrong as Jim Singer

Mikey Madison as Kathleen

Christopher Rodriguez Marquette as Craig

Ashlyn Faith Williams as Hillary

Lindsey Kraft as Tobey

Dendrie Taylor as Jessica

Bella Pellington as Marie

Shinelle Azoroh as Waitress

Tiffany Dion as Kathleen's Friend

Chloe Farnworth as Actress

Tamar Pelzig as Actress

Patton Oswalt as Kathleen's Father