Zoe Saldaña as Sarah Cotton

Rosamund Pike as Dedra Davenport

Lake Bell as Maryjane

Paz Vega as Blanca Juarez

Shannen Doherty as Dr. Shelly

Nick Stahl as Robert Kane

Emily Meade as Chloe Marx

Robert Hoffman as Chad Bower

Jamie Chung as Ginny Bai

Dylan McDermott as Dennis Marx

Colleen Camp as Barbara Barish

Anson Mount as Tom

Ross Thomas as Lukas

Jon Polito as The Phamacist

Victor Webster as Paulo Small

Peter Macdissi as Gerry

Tiara McKinney as Mahogany

Adriana Barraza as Louisa Alvarez

Jake Austin Walker as Trevor

Addison Black as Colby

Chandler George Brown as Jeffrey

Naz Jafri as Dr. Pakora

Victoria Patenaude as Bag Lady

Jonathan McDaniel as Trey

Jim Lau as Tak Bai

Scott Lunsford as Stud

Jason Brooks as Steve

Haley Tju as Rose

Kate Albrecht as Tammy Lynn

Cici Lau as Soon Li

Fabian C. Moreno as Hector

Tom Wright as Maxwell Barron

C.K. McFarland as Woman

Dimitri Diatchenko as Bob

Aron Biedenharn Coates as Tammy

Lisa Marie Dupree as Busty Waitress

Cherie Thibodeaux as Girl #1

Edrick Browne as Medical Center Guard

Austin Williams as Nicholas Pinter

Monica Acosta as Birthday Party Mom

Daurice Cummings as Club Dancer

Aurelius DiBarsanti as Geisha House Waiter

Carol Dupuy as Apartment Tenant

Louis Dupuy as Apartment Tenant

Jerald Garner as Restaurant Patron / Dancer

Adam Knapp as Party Guy

Michelle Lenhardt as Beautiful Woman

Kelly Migdon as Student

Marcus Morales as Restaurant Customer

Gabriela Ostos as Cashier

Ross Rouillier as Orderly

Aaron Sauer as Orderly

Jabari Simba as Gym Patron

Deanna Tryon as Flight Attendant

Valerie Joy Wilson as Club Dancer

Jackie Zane as Caretaker