Anthony Conti as Jacob Aceto

J.K. Simmons as Ralph Aceto

Laura Dern as Doctor

David Lynch as Man In Black

Richard Chamberlain as Creepy Oncologist

Johnny Depp as Nuclear Med Tech

John Grady as Blackened Corpse

Jade Pettyjohn as Bri Alonso

Chad L. Coleman as Tanner Alonso

Keith Allan as Jonathan King

Pritesh Shah as Beemo

Penelope Ann Miller as Ghiandola Anita Aceto

Nancy Berggren as Elderly Ghiandola

Lisa Roumain as Decayed Ghiandola

Gary D. Hancock as Petrified Ghiandola

Jes Selane as Rotted Ghiandola

Keith Sclon as Schoolboy Ghiandola

Maria Huggins as Teenage Ghiandola

Eloisa Huggins as Young Ghiandola

Olivia Simmons as Schoolgirl Ghiandola