River Phoenix as Mike Waters

Keanu Reeves as Scott Favor

James Russo as Richard Waters

William Richert as Bob Pigeon

Rodney Harvey as Gary

Chiara Caselli as Carmella

Michael Parker as Digger

Jessica Makinson as Denise

Flea as Budd

Grace Zabriskie as Alena

Tom Troupe as Jack Favor

Udo Kier as Hans

Sally Curtice as Jane Lightwork

Robert Lee Pitchlynn as Walt

Mickey Cottrell as Daddy Carroll

Wade Evans as Wade

Matthew Ebert as Coverboy

Scott Patrick Green as Coverboy / Cafe Kid

Tom Cramer as Coverboy

Vana O'Brien as Sharon Waters

Shaun Jordan as Cafe Kid

Shawn Wight as Cafe Kid

George Conner as Bad George

Oliver Kirk as Indian Cop

Stanley Hainsworth as Dirtman

Joshua Halladay as Baby Mike

Douglas Tollenen as Little Richard

Steven Clark Pachosa as Hotel Manager

Lannie Swerdlow as Disco Manager

Wally Gaarsland as Rock Promoter

Bryan Wilson as Rock Promoter

Mark Weaver as Rock Promoter

Conrad 'Bud' Montgomery as Rock Promoter

Pat Patterson as Cop

Steve Vernelson as Cop

Mike Cascadden as Cop

Eric Hull as Mayor's Aid

James A. Arling as Minister

Jim Caviezel as Airline Clerk

Ana Cavinato as Stewardess

Melanie Mosely as Lounge Hostess

Greg Murphy as Carl

David Reppinhagen as Yuppie at Jake's

Tiger Warren as Tiger Warren

Massimo Di Cataldo as Italian Street Boy

Pao Pei Andreoli as Italian Street Boy

Robert Egon as Italian Street Boy

Paolo Baiocco as Italian Street Boy

Mario Stracciarolo as Mike's Italian Client

Gus Van Sant as Man Behind Hotel Counter (uncredited)