Madison Pettis as Kitty Purry (voice)

David DeLuise as Steven

Jed Rees as Roland

Danny Woodburn as Butch (voice)

Mackenzie Sol as P.U.P. (voice)

Denisse Ojeda as Ida

Kaitlyn Maher as Tiny / Scrappy (voice)

Jacob MacLeod as Presenter at Awards Show

Reggie De Leon as Shep

Dave Coulier as Jimmy Kibble (voice)

Makenzie Moss as Lou

Tatiana Gudegast as Heidi (voice)

Diedrich Bader as Kano (voice)

George Newbern as Bark (voice)

Cameron Hughes as Taxi Driver / Mutt (voice)

Benjamin Flores Jr. as M.C. Bite (voice)

Josh Flitter as Ruff (voice)

Ken Lawson as Garbage Man

Michael Teigen as Him

Adele Jacques as Coiffure (voice)

Lombardo Boyar as Security Guard Dog (voice)

Sheridan Smith as Dalmatian Reporter (voice)

Jonathan Mangum as Rover (voice)

Nikki Blonsky as Lady Paw Paw (voice)

Ziggy Marley as Dog Gnarly (voice)

Obba Babatundé as Big Ears (voice)

Steve Valentine as Simon Growl (voice)

Jessica Mona Johnston as Street Artist (voice)

Matty Finochio as Guido

Randy Petersen as Shampoo (voice)

Danni Rosner as Prissy / Mother (voice)

Brian Hull as James Corgie (voice)

Jeremy D. Howard as Magic

Chris Coppola as Rocky (voice)

Tom Everett Scott as Charlie (voice)

Molly Burnett as Emily (voice)

John Ratzenberger as Salty (voice)