Rajinikanth as Padayappa

Sivaji Ganesan as Dharmalingam

Ramya Krishnan as Neelambari

Soundarya as Vasundhara

Lakshmi as Savithri

Sithara as Nandhini

Radha Ravi as Rajarathnam

Nassar as Surya Prakash

Manivannan as Ramalingam

Senthil as Alagapuri Azhagesan

Abbas as Chandra Prakash

Preetha Vijayakumar as Anitha

Anu Mohan as Chinnarasu

Ramesh Khanna as Murugesan

Vadivukarasi as Kamatchi

Sathyapriya as Sivagami

Mansoor Ali Khan as Krishnaswamy Mudaliar

Prakash Raj as Police Officer

Vasu Vikram as Shanmugavel

Raja Ravindra as Saravanavel

Rajesh Kumar as Sivaraman

Vijay Sarathy as Sarathi

Lavanya as Meena

Anitha as Savitha

Idichapuli Selvaraj as Village man

Ravi Raghavendra as Ravi Chellaiah

Raja Bagadur as Raja Bagadur

Kanal Kannan as Farmer told by Neelambari to kill the snake

Tirupur Ramasamy as Village man

Kovai Senthil as Village man

Mohan Raman as Lawyer Rangarajan

Nellai Siva as Village man

Scissor Manogar as Village man

Savitha Reddy as Vasundhara (voice)

Mahendran as Kid at Anitha's birthday (uncredited)

Robo Shankar as Dancer in the song "En Peru Padayappa" (uncredited)

Aravind Akash as Dancer in the song "En Peru Padayappa" (uncredited)

K. S. Ravikumar as Guest at Anitha's birthday (Cameo Appearence)