Gena Rowlands as Mildred

Marisa Tomei as Monica

Gérard Depardieu as Big Tommy

Jake Lloyd as J.J.

Moira Kelly as Ann Mary Margaret

David Sherrill as Ethan

David Thornton as Frankie

Bridgette Wilson-Sampras as Jeannie

Bobby Cooper as Bernt

Clint Howard as Gus

David Rowlands as George

Jamie Bozian as Jason

Christy Lenk as Miss Mannis

Brittney Lewis as Hospital Receptionist

Vinnie Curto as Danny

D. Chance Williams as Bartender

Gérard L'Heureux as Mover

Tom Proctor as Duncan

Dru Homer as Bar Patron

Barby Garcia as Airline Attendant (uncredited)

Frank Gerrish as Shoe Salesman (uncredited)

Christopher Robin Miller as Drunk Bar Patron (uncredited)

Joseph Quinn Simpkins as Businessman (uncredited)

James Woodson as Bar Patron (uncredited)

Dennis W. Zerull as Drunken Man (uncredited)