Sally Hawkins as Jane

David Thewlis as Mike

Alice Lowe as Alice

Billie Piper as Nicola

Penelope Wilton as Vivian

Robert Pugh as Dennis

Banita Sandhu as Alex

Paul Hilton as Tony

Morfydd Clark as Young Jane

Natalie O'Neill as Young Nicola

Elysia Welch as Young Alice

Boyd Clack as Doctor

Robert Aramayo as Lover's Voice (voice)

Rita Bernard-Shaw as Lucy

Tony Leader as Lesley

Spencer Deere as Jack

Amelie Tukandra as Nurse

Nicholas Lumley as Photographer

Kas Meghani as Examiner