Simon Pegg as William Burke

Andy Serkis as William Hare

Isla Fisher as Ginny

Georgia King as Emma

Tom Wilkinson as Dr. Knox

Tim Curry as Dr. Monroe

Christopher Lee as Old Joseph

Jessica Hynes as Lucky

Bill Bailey as Angus

Stephen Merchant as Footman

Hugh Bonneville as Lord Harrington

David Schofield as Fergus

Allan Corduner as Nicephore

Pollyanna McIntosh as Mary

Ronnie Corbett as Captain Tam McLintoch

Michael Smiley as Patterson

David Hayman as Danny McTavish

Reece Shearsmith as Sergeant Mackenzie

Steve Speirs as McMartin's Doorman

John Woodvine as Lord Provost

Duncan Duff as Attendent

Max Landis as Handsome Coachman

Joseph Dewey as Medical Student

Ciaron Kelly as Private Fox

Michael Winner as Gentleman Passenger

Ray Harryhausen as Distinguished Doctor

Simon Farnaby as William Wordsworth

Tom Meeten as Samuel Coleridge

Paul Whitehouse as Gentleman Drunk

Tom Urie as Heart Attack Man

Ella Smith as Barmaid

Janet Whiteside as Old Woman

Jenny Agutter as Lucy

Chris Obi as John Martin

Michael Billington as Medical Student

Billy Riddoch as Rabble Rouser

Costa-Gavras as French Family

Michèle Ray-Gavras as French Family

Romain Gavras as French Family

Emmanuel Hamon as French Family

Theo Hamon as French Family

Jacob Edwards as Hollyrood Courtier