Charlize Theron as Aileen Wuornos

Christina Ricci as Selby Wall

Bruce Dern as Thomas

Lee Tergesen as Vincent Corey

Annie Corley as Donna

Pruitt Taylor Vince as Gene / Stuttering "John"

Marco St. John as Evan / Undercover "John"

Marc Macaulay as Will / Daddy "John"

Scott Wilson as Horton / Last "John"

Rus Blackwell as Cop

Tim Ware as Chuck

Stephan Jones as Lawyer

Brett Rice as Charles

Kaitlin Riley as Teenage Aileen

Cree Ivey as 7-Year-Old Aileen

Catherine Mangan as Justy

Magdalena Manville as Bar Lap Girl

T. Robert Pigott as Bartender

Romonda Shaver as Employment Agent

Glenn R. Wilder as Restaurant Manager

Elaine Stebbins as Wife at Accident

Kane Hodder as Undercover Cop

Christian Stokes as Undercover Cop

Lyllian Barcaski as Bar Girl

Nonalee Davis as Bar Girl

Bubba Baker as Cubby

Al as Himself

Cannonball as Himself

Chad Vaccarino as Trevor

Gene R. Stephenson as Judge

Jesse Stern as Skate Rink Attendant

Billy Boylan as Police Chief

Jim R. Coleman as Newscaster

Chandra Leigh as Cute Teenage Attendant

Lori McDonald as Attendant

Adam Brown as Attendant

Ed Donovan as State Prison Guard (uncredited)