Tom Hanks as Hero Boy / Father / Conductor / Hobo / Scrooge / Santa Claus

Leslie Zemeckis as Sister Sarah / Mother

Eddie Deezen as Know-It-All

Nona Gaye as Hero Girl (voice)

Peter Scolari as Billy - Lonely Boy

Michael Jeter as Smokey / Steamer

Josh Hutcherson as Hero Boy (motion capture)

Daryl Sabara as Hero Boy (voice)

Jimmy Bennett as Lonely Boy (voice)

Tinashe as Hero Girl (motion capture)

Brendan King as Pastry Chef

Andy Pellick as Pastry Chef

Josh Eli as Waiter

Mark Mendonca as Waiter

Rolondas Hendricks as Waiter

Mark Goodman as Waiter

Jon Scott as Waiter

Gregory Gast as Waiter

Sean Scott as Waiter

Gordon Hart as Waiter

Chris Coppola as Toothless Boy / Elf

Julene Renee as Red Head Girl / Elf

Charles Fleischer as Elf General

Steven Tyler as Elf Lieutenant / Elf Singer

Phil Fondacaro as Elf

Debbie Lee Carrington as Elf

Mark Povinelli as Elf

Ed Gale as Elf

Dante Pastula as Little Boy

André Sogliuzzo as Smokey / Steamer (voice)

Isabella Peregrina as Sister Sarah (voice)

Eric Newton as Acrobatic Elf

Aidan O'Shea as Acrobatic Elf

Aaron Hendry as Acrobatic Elf

Kevin C. Carr as Acrobatic Elf

Bee Jay Joyer as Acrobatic Elf

Jena Carpenter as Acrobatic Elf

Karine Mauffrey as Acrobatic Elf

Elisabeth P. Carpenter as Acrobatic Elf

Bill Forchion as Acrobatic Elf

Devin Henderson as Acrobatic Elf

Sagiv Ben-Binyamin as Acrobatic Elf

Ashly Holloway as Sister Sarah

Jimmy 'Jax' Pinchak as Know-It-All

Chantel Valdivieso as Hero Girl

Hayden McFarland as Lonely Boy

Connor Matheus as Toothless Boy

Evan Sabara as Young Boy

Jack Angel as Wolves (uncredited)

Rodger Bumpass as Wolves (uncredited)

Dylan Cash as Boy (voice) (uncredited)

Cody Klop as Additional Voices (voice) (uncredited)

Patrick Stogner as (uncredited)