Demi Moore as Lucy

Jessica Williams as Jess

Ed Helms as Brandon

Karan Soni as Freddie

Dan Bakkedahl as Billy

Isiah Whitlock, Jr. as Derek

Jennifer Kim as May

Martha Kelly as Gloria

Calum Worthy as Aidan

Nasim Pedrad as Suzy

Jim Meskimen as Pegasus Gary

Leland Orser as Rescue Team Leader

Chris Harding as Bobby Skylar

Wendy Meredith as Victoria

Frank Bond as Ian

Courtney Cunningham as Olivia

Britney Spears as Self (voice)

Kate Pierson as Psychedelic Dream Creature (voice)

Fred Schneider as Psychedelic Dream Creature (voice)

Keith Strickland as Psychedelic Dream Creature (voice)

Cindy Wilson as Psychedelic Dream Creature (voice)

Mel Mel Sukekawa-Mooring as Additional Psychedelic Dream Creatures (voice)

LynNita Ellis as Reporter (uncredited)

David Phyfer as Deputy Sheriff (uncredited)