Marisa Tomei as Evie

Rob Morrow as Matthew Heller

Mathilda May as Silvia Rinaldi

Jeroen Krabbé as Francois

Georges Corraface as Nico Rinaldi

Paul Freeman as Dallesandro

Emmy Rossum as Lily

Ellen Muth as Rachel

Sharon Holm as Barbara Lipton

Natacha Lindinger as Denise

Jonathan Aris as Emil Becker

Kate Harper as Dr. Hiller's Receptionist

Jay Benedict as Roger

Cyril Nri as Eric Blair

Michiel Nooter as Gerrit Kleiman

Rodney Beddal as Dino

Sylvia Rotter as Anna-Maria

Jeffery Kissoon as Rashid

Nro Tlahapi as African Nurse

Mirjam de Rooij as Amsterdam Desk Clerk

Soukusa as Translator

Nthati Moshesh as Pregnant Woman

Magic Hlatshwayo as Leper

Peter Mkubheka as Man with Gangrene

Michael Shannon as Dr. Duncan

Mark Leake as Greg Lipton

Louis Condon as Joshua Lipton

Shane Rimmer as Warren Oliver

Alessandra Scott as Italian Reporter

Jana Shelden as Doris

Ben Miles as Radiologist

Lee Ross as Technician

Miles Condon as Joshua Lipton

Mathijs Schaap as Laboratory technician/anesthesisy