Viola Davis as Ma Rainey

Chadwick Boseman as Levee

Colman Domingo as Cutler

Glynn Turman as Toledo

Michael Potts as Slow Drag

Jeremy Shamos as Irvin

Jonny Coyne as Sturdyvant

Taylour Paige as Dussie Mae

Dusan Brown as Sylvester

Joshua Harto as Policeman

Quinn VanAntwerp as Band Singer

Chloe Davis as Ma Rainey's Dancer

Mayte Natalio as Ma Rainey's Dancer

Johanna Elmina Moise as Ma Rainey's Dancer

Onyxx Noel as Ma Rainey's Dancer

LaWanda Hopkins as Ma Rainey's Dancer

Sierra Stewart as Ma Rainey's Dancer

Malaiyka Reid as Ma Rainey's Dancer

Catherine Foster as Ma Rainey's Dancer

Antonio Fierro as Laborer (uncredited)

Daniel Johnson as Chicago Worker (uncredited)