Sam Rockwell as Wolf (voice)

Marc Maron as Snake (voice)

Awkwafina as Tarantula (voice)

Craig Robinson as Shark (voice)

Anthony Ramos as Piranha (voice)

Richard Ayoade as Professor Marmalade (voice)

Zazie Beetz as Diane Foxington (voice)

Alex Borstein as Police Chief Misty Luggins (voice)

Lilly Singh as Tiffany Fluffit (voice)

Barbara Goodson as Old Lady (voice)

Dina Morrone as Museum Announcer / Diane's A.I. Assistant (voice)

Michael Godere as Delivery Driver / Museum Guest 1 (voice)

Kelly Cooney Cilella as Prison Guard 1 / Gala Guest 1 (voice)

Walt Dohrn as Scientist / Gala Guest 3 (voice)

David P. Smith as Prison Guard 2 / Gala Guest 2 / Protestor (voice)

John Venzon as Museum Guest 2 / Panicked Cop (voice)

Jesse Averna as Prison Guard 3 (voice)