Zachary Levi as Kurt Warner

Anna Paquin as Brenda Meoni/Brenda Warner

Hayden Zaller as Zack

Ser'Darius Blain as Mike Hudnutt

Dennis Quaid as Dick Vermeil

Chance Kelly as Mike Martz

Simeon Castille as Isaac Bruce

Bruce McGill as Jim Foster

Adam Baldwin as Coach Allen

Cindy Hogan as Sue Warner

Steven Chester Prince as Gene Warner

Jason Allen Wear as Stadium Security

Aaron J. Brooks as Hy-Vee Customer

Garrett O'Brien as Stadium Security

Bryce Bruckbauer as Young Matt Warner

Collin Taylor as #87 Ricky Proehl

Beau Hart as Young Kurt Warner

Bryce Barfield as Opposing College Head Coach (uncredited)

Trisha Zarate as Hy-Vee Cashier