Seth MacFarlane as Peter Griffin as Han Solo / Brian Griffin as Chewbacca / Stewie Griffin as Darth Vader / Glenn Quagmire as C-3PO / Tom Tucker as Imperial Newscaster / Carter Pewterschmidt as Uncle Owen / Safeguard #1 / Italian #2 / White Guard #2 (voice)

Alex Borstein as Lois Griffin as Princess Leia / Barbara Pewterschmidt as Aunt Beru (voice)

Seth Green as Chris Griffin as Luke Skywalker (voice)

Mila Kunis as Meg Griffin (voice)

Mike Henry as Cleveland Brown as R2-D2 / John Herbert as Obi-Wan Kenobi / Bruce the Performance Artist as Greedo / Fouad as Imperial Officer (voice)

Lori Alan as Diane Simmons as Imperial Newscaster (voice)

Rush Limbaugh as Himself / Red 6 (voice)

Tom Baker as The Doctor (archive footage)

Mark Hentemann as Opie as Tusken Raider (voice)

Phil LaMarr as Ollie Williams as Imperial Meteorologist / Redd Fox (voice)

John Viener as TV Announcer / Black Guard / Spaceguard #1 / White Guard #1 / Vader Guard #2 / Sean Connery (voice)

Leslie Nielsen as Dr. Rumack (archive voice)

Patrick Warburton as Joe Swanson as Biggs Darklighter (voice)

John G. Brennan as Mort Goldman as Jawa (as Johnny Brennan)

Steve Callaghan as Rebel Soldier (voice)

Chevy Chase as Clark Griswold (voice)

Beverly D'Angelo as Ellen Griswold (voice)

Mick Hucknall as Himself (voice)

Helen Reddy as Herself (voice)

Danny Smith as Vader Assistant 2 / Italian 1 / Vade Guard 1 / Darth Harrington (voice)

Alec Sulkin as Various Characters (voice)

Don Thai Theerathada as Thai Pilot (voice) (as Don Tai)

Adam West as Mayor Adam West as Grand Moff Tarkin (voice)

Judd Nelson as John Bender (uncredited) (voice)