Ben Stiller as Greg Focker

Robert De Niro as Jack Byrnes

Dustin Hoffman as Bernie Focker

Barbra Streisand as Rozalin Focker

Blythe Danner as Dina Byrnes

Teri Polo as Pam Byrnes

Owen Wilson as Kevin Rawley

Spencer Pickren as Little Jack 'L.J.' Byrnes

Bradley Pickren as Little Jack 'L.J.' Byrnes

Alanna Ubach as Isabel Villalobos

Ray Santiago as Jorge Villalobos

Tim Blake Nelson as Officer LeFlore

Shelley Berman as Judge Ira

Kali Rocha as Flight Attendant

Dorie Barton as Airline Clerk

Jack Plotnick as Rent-a-Car Agent

Wayne Thomas Yorke as Airport Security Guard

B.J. Hansen as B.J.

J.P. Manoux as Local Cop

Myra Turley as Admitting Nurse

Vahe Bejan as Gunther - Immigrant Man

Kathleen Gati as Venka - Immigrant Woman

Angelo Tiffe as Businessman

Kyle T. McNamee as Undercover Waiter

Cedric Yarbrough as Prison Guard

Max Hoffman as Woody Focker

Benjamin Trueblood as Newborn Baby

Roberto Garcia as Waiter

Bruno Coon as Strolling Minister / Band Member

Rock Deadrick as Wedding Band

David Sutton as Wedding Band

Bernadette Pérez as Girl Bus Driver

Linda O'Neil as Girl on Bus

Tiffany Turner as Girl on Bus

David Zimmerman as Dom Focker (uncredited)

Angela Casassa as Girl at Wedding (uncredited)

Victoria Chalaya as Pam's Cousin (uncredited)

Karen-Eileen Gordon as Anita Focker (uncredited)

Fabrizio Imas as Chicken Man (uncredited)

Angie Jaree as Bunny Focker (uncredited)

Sarah Kane as Senior Yoga Class Attendee (uncredited)

R. Martin Klein as Mo Focker (uncredited)

Allan Kolman as Harry Focker (uncredited)

Sean LoGrasso as Party Guest (uncredited)

Chris Mala as Wedding Guest (uncredited)

Rana McAnear as Party Guest (uncredited)

Connie Richmond as Frida Focker (uncredited)

Antonio Rufino as Waiter (uncredited)

Jimmy Star as Party Guest (uncredited)

Scott Stewart as Pedestrian (uncredited)